Our Solutions – Overview
Dialysis – Four Factors Drive Needs
Dialysis is a lifesaving treatment. However, dialysis also exerts metabolic, inflammatory and other adverse effects on different organs, such as the cardiovascular system.
In case of PD, the time span in which dialysis may be performed is limited by fibrotic changes in the peritoneal tissue. It is therefore anticipated that by ameliorating these effects not only the duration of PD can be prolonged but overall, the inflammatory burden of disease on the patient can be reduced. Therefore, it seems that a lot may be achieved, by “softening” dialysis treatment.
Opterion applies different strategies to this goal:
- Reducing osmotic pressure during PD dwells without compromising ultrafiltration efficacy.
- Eliminating glucose from PD solutions to avoid metabolic burden.
- Decrease cytotoxicity of PD solutions to the peritoneum, reducing fibrosis, with the goal to prolong PD treatment time.
- Osmotic Driver (ODR) designed to offer flexibility in short and long dwell times.
Peritoneal dialysis (PD) uses the body’s own peritoneal membrane within the abdomen as the filter to clean the blood. This procedure is quite gentle and can be self-administered at home or on the move. PD treatment is performed on a daily basis and integrated in an active life.
We believe that with the Opterion solutions, insulin dosage and glucose related diabetic challenges can be reduced.